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. 2024 Jun 26;15:1416530. doi: 10.3389/fendo.2024.1416530

Table 2.

Baseline characteristics of population divided by TyG index-related situation.

Characteristics Overall
(n=596)
High TyG index
(n=304)
Low TyG index
(n=292)
P value
Age (years) 71.71 ± 9.36 71.19 ± 9.67 72.26 ± 9.01 0.161
Male, n (%) 212(35.57%) 101(33.22%) 111(38.01%) 0.222
BMI (kg/m2) 24.53 ± 3.64 25.30 ± 3.72 23.72 ± 3.37 <0.01
Smoking n (%) 147(24.66%) 73(25.00%) 74(24.34%) 0.852
SBP (mmHg) 133.56 ± 19.16 134.10 ± 19.13 133.00 ± 19.20 0.486
DBP (mmHg) 75.62 ± 11.21 75.46 ± 11.20 75.78 ± 11.25 0.733
Laboratory variables
 TC (mmol/L) 3.86(3.26~4.57) 4.10(3.41~4.98) 3.64(3.13~4.21) <0.01
 TG(mmol/L) 1.31(0.96~1.92) 1.91(1.45~2.33) 0.97(0.80~1.18) <0.01
 HDL-C(mmol/L) 1.22(1.00~1.47) 1.15(0.95~1.36) 1.29(1.06~1.62) <0.01
 LDL-C(mmol/L) 2.26(1.72~2.87) 2.43(1.91~3.13) 2.13(1.65~2.64) <0.01
 FBG(mmol/L) 5.82(5.05~7.63) 7.14(5.68~9.31) 5.27(4.79~5.84) <0.01
 HbA1c(%) 5.80(5.40~6.80) 6.30(5.50~7.50) 5.50(5.30~6.00) <0.01
 TyG index 8.80(8.36~9.26) 9.25(8.98~9.58) 8.34(8.12~8.55) <0.01
Case history
 Hypertension n (%) 467(78.36%) 239(78.62%) 228(78.08%) 0.874
 T2DM n (%) 292(48.99%) 196(64.47%) 96(32.88%) <0.01
 Dyslipidemia n (%) 388(65.10%) 204(67.11%) 184(63.01%) 0.295
 Prior CVDs n (%) 506(84.90%) 250(82.24%) 256(87.67%) 0.064
 Prior PCI n (%) 161(27.01%) 89(29.28%) 72(24.66%) 0.204
 Prior stroke n (%) 264(44.30%) 144(47.37%) 120(41.10%) 0.123
 Family history of CVDs n (%) 183(30.70%) 98(32.24%) 85(29.11%) 0.408
Medications
 Antiplatelet medication n (%) 565(94.80%) 285(93.75%) 280(95.89%) 0.239
 ACEI/ARB n (%) 262(43.96%) 162(53.29%) 100(34.25%) <0.01
 CCB n (%) 334(56.04%) 175(57.57%) 159(54.45%) 0.444
 β-Blocker n (%) 351(58.89%) 181(59.54%) 170(58.22%) 0.743
 Antidiabetic agents n (%) 253(42.45%) 183(60.20%) 70(23.97%) <0.01
 Statins n (%) 516(86.58%) 277(91.12%) 239(81.85%) <0.01
 Antidepressants n (%) 405(67.95%) 198(65.13%) 207(70.89%) 0.132
 Benzodiazepines n (%) 214(35.91%) 109(35.86%) 105(35.96%) 0.979

BMI, body mass index; SBP, systolic blood pressure; DBP, diastolic blood pressure; TC, total cholesterol; TG, triglyceride; LDL-C, low-density lipoprotein cholesterol; HDL-C, high-density lipoprotein cholesterol; FBG, fasting blood glucose; HbA1c, glycosylated hemoglobin; TyG, triglyceride-glucose;T2DM, diabetes mellitus type 2; CVD, cardiovascular disease; PCI, percutaneous coronary intervention; ACEI, angiotensin converting enzyme inhibitor; ARB, angiotensin receptor blocker; CCB, calcium channel blocker.