Table 4.
Preoperative CA-125 cut-off values, optimal cytoreduction rate and overall survival rate of all included studies
| Study | Author | Intervention | RoB | CA-125 cut-off value (U/ml) | Optimal cytoreduction rate (%) | OS rate (%) | Sensitivity for optimal cytoreduction (%) | Specificity for optimal cytoreduction (%) | p-value |
|---|---|---|---|---|---|---|---|---|---|
| 1 | Matsahashi et al. [31] | NACT-IDS | M | 3 5 | 78.1 | 78 | 78.0 | 68.0 | 0.01 |
| 2 | Prajatmo et al. [28] | NACT-IDS | L | 7 0 | 65.5 | 86 | - | - | |
| 3 | Gupta et al. [38] | NACT-IDS | M | 100 | 55 | - | - | - | <0.001 |
| 4 | Merlo et al. [32] | NACT-IDS | M | 500 | 71.6 | - | 58.0 | - | 0.002 |
| 5 | Parakeshvova et al.[34] | SCS | M | 164 | 58.5 | 46.3 | 58.5 | 66.9 | 0,002 |
| 6 | May et al. [35] | PDS | M | 174 | 70.3 | 77.6 | - | - | 0.001 |
| 7 | Muallem et al. [35] | PDS | L | 252 | 79.1 | 62 | 79.1 | 55.1 | - |
| 8 | Bachmann et al. [29] | PDS | M | 500 | 74.3 | 74.3 | - | - | 0.023 |
| 9 | Bai et al. [33] | PDS | M | 1066 | 89.9 | 76.9 | - | - | 0.654 |