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. 2024 Jun 21;16(13):2289. doi: 10.3390/cancers16132289
AOI area of illumination
APC antigen presenting cells
CNN convolutional neural networks
CP Cellpose
DSP digital spatial profiler
IA image analysis
IHC immunohistochemistry
LMM linear mixed models
MCL mantle cell lymphoma
mIF multiplexed immunofluorescent images
ns nonsignificant
ROI region of interest
SDI Shannon-Wiener Diversity Index (SDI)
T57+/T57− ratio of CD3+ CD57+ T-cells over CD3+ CD57− T-cells
TC CD3+ CD8+ Cytotoxic T-cells
TC,57− CD3+ CD8+ CD4+ CD57− Cytotoxic T-cells
TC,57+ CD3+ CD8+ CD4+ CD57+ Cytotoxic T-cells
TH CD3+ CD4+ Helper T-cells
TH,57− CD3+ CD8− CD4+ CD57− Helper T-cells
TH,57+ CD3+ CD8− CD4+ CD57+ Helper T-cells
TH/TC Ratio of CD3+ CD4+ Helper T-cells over CD3+ CD8+ Cytotoxic T-cells
TIME tumor-immune microenvironment
TMA tissue microarray
TME tumor microenvironment
TR tumor-rich
Tregs regulatory T cells
TS tumor-sparse
U-NET U-type convolutional neural networks