Table 2.

Univariate analysis of cadherins’ expression profile in glioblastomas and association with patient’s prognosis.

		Progression-Free Survival				Overall Survival
		HR	95.0% CI		p-Value	HR	95.0% CI		p-Value
			Inferior	Superior			Inferior	Superior
Surgery	Surgery	1				1
	Biopsy	2.120	1.626	2.763	<0.001	2.329	1.842	2.945	<0.001
Treatment	Yes	1				1
	No	13.244	8.492	20.665	<0.001	4.730	3.547	6.308	<0.001
KPS	100	1				1
	50	0.505	0.056	4.550	0.543	1.772	1.183	2.654	0.006
	60	0.580	0.078	4.318	0.595	1.411	0.866	2.298	0.167
	70	0.587	0.080	4.295	0.600	2.575	1.223	5.421	0.013
	80	0.430	0.059	3.105	0.403	2.596	1.035	6.508	0.042
	90	0.391	0.054	2.826	0.352	1.599	1.022	2.503	0.040
Age	< 65 yo	1				1
	> 65 yo	1.258	0.974	1.625	0.079	1.400	1.113	1.762	0.004
Ncad	Negative	1				1
	Positive	0.725	0.522	1.007	0.055	0.627	0.468	0.840	0.002
Ecad	Negative	1				1
	Positive	0.716	0.546	0.938	0.016	0.779	0.608	0.998	0.048
Pcad	Negative	1				1
	Positive	1.367	1.003	1.863	0.048	1.364	1.029	1.806	0.031
Cadherins co-expression	Ecad/Ncad	1				1
	Ncad	1.367	0.984	1.900	0.063	1.316	0.969	1.787	0.079
	Ecad	1.507	0.471	4.826	0.490	2.550	0.923	7.041	0.071
	Pcad	1.864	0.884	3.933	0.102	2.611	1.239	5.502	0.012
	Pcad/Ncad	1.910	1.186	3.076	0.008	1.619	1.033	2.536	0.036
	Ecad/Pcad	2.203	1.068	5.868	0.035	2.728	1.169	6.366	0.020
	Triple positive	1.194	0.683	2.087	0.533	1.427	0.875	2.328	0.154
	Triple negative	1.712	1.084	2.704	0.021	1.794	1.196	2.690	0.005