Table 1.
Characteristics of study participants <70 years of age grouped according to body mass index and metabolic status.
| BMI < 25 kg/m2 | BMI ≥ 25 kg/m2 | ||||||||
|---|---|---|---|---|---|---|---|---|---|
| Metab− N = 983 |
Metab+ N = 3604 |
Metab− N = 438 |
Metab+ N = 6560 |
||||||
| Variable | Mean | SD | Mean | SD | Mean | SD | Mean | SD | p-Value |
| Age, years | 40.9 | 11.7 | 51.5 | 12.1 | 46.9 | 12.1 | 54.1 | 10.9 | <0.001 |
| BMI, kg/m2 | 21.7 | 2.0 | 22.7 | 1.7 | 27.9 | 3.0 | 29.1 | 3.5 | <0.001 |
| Office SBP, mmHg | 114.6 | 8.8 | 139.2 | 21.7 | 117.1 | 8.2 | 141.8 | 21.0 | <0.001 |
| Office DBP, mmHg | 71.9 | 6.7 | 84.7 | 12.6 | 74.1 | 6.2 | 86.0 | 12.3 | <0.001 |
| Heart rate, bpm | 68.6 | 10.8 | 72.4 | 12.5 | 67.7 | 10.4 | 72.4 | 12.2 | <0.001 |
| Glucose, mg/dL | 82.5 | 7.2 | 92.1 | 16.4 | 85.2 | 7.4 | 98.2 | 22.2 | <0.001 |
| Triglycerides, mg/dL | 73.9 | 27.3 | 106.8 | 60.6 | 83.9 | 30.4 | 135.9 | 79.3 | <0.001 |
| Uric acid, mg/dL | 4.2 | 1.0 | 4.5 | 1.3 | 4.7 | 1.3 | 5.1 | 1.3 | <0.001 |
| Total cholesterol, mg/dL | 200.8 | 37.7 | 209.4 | 39.6 | 208.4 | 37.5 | 215.9 | 38.8 | <0.001 |
| HDL-cholesterol, mg/dL | 63.4 | 13.4 | 55.6 | 15.1 | 59.1 | 12.4 | 50.1 | 13.1 | <0.001 |
| LDL-cholesterol, mg/dL | 122.7 | 34.9 | 132.4 | 35.5 | 132.4 | 34.5 | 138.5 | 35.8 | <0.001 |
| Sex, males, % | 42.2 | ---- | 49.3 | ---- | 47.0 | ---- | 49.0 | ---- | 0.001 |
| Smoker or ex-smoker, % | 33.9 | ---- | 36.8 | ---- | 34.9 | ---- | 37.3 | ---- | 0.17 |
| Anti-HT treatment, % | 8.8 | ---- | 28.1 | ---- | 17.6 | ---- | 37.8 | ---- | <0.001 |
| Alcohol, yes (N = 10,047), % | 35.6 | ---- | 53.9 | ---- | 44.7 | ---- | 59.2 | ---- | <0.001 |
| Sedentary, (N = 8124), % | 50.9 | ---- | 58.6 | ---- | 50.3 | ---- | 61.6 | ---- | <0.001 |
| High waist circ, (N = 8113), % | 2.4 | ---- | 7.5 | ---- | 32.2 | ---- | 44.0 | ---- | <0.001 |
| MACE, % | 0.5 | ---- | 5.7 | ---- | 2.7 | ---- | 7.4 | ---- | <0.001 |
BMI indicates body mass index; Metab−, subjects with no abnormal metabolic parameter; Metab+, subjects with at least one abnormal metabolic parameter; SBP, systolic blood pressure; DBP, diastolic blood pressure; Anti-HT, antihypertensive; MACE, major adverse cardiovascular events; circ, circumference. p-values for continuous variables from ANCOVA, adjusted for age and sex.