Table 2.
Multivariable Cox model for risk of major adverse cardiovascular events in the participants <70 years of age categorized according to BMI (3 categories) and metabolic status.
| Group | Estimate | Standard Error | Wald Chi2 | p-Value | Hazard Ratio |
95% Confidence Limit |
|---|---|---|---|---|---|---|
| BMI < 25.0 Metab+ |
1.93 | 0.45 | 18.12 | <0.0001 | 6.92 | 2.84 to 16.86 |
| BMI = 25.0–29.9 Metab− |
1.22 | 0.56 | 4.75 | 0.029 | 3.38 | 1.13 to 10.11 |
| BMI = 25.0–29.9 Metab+ |
1.95 | 0.45 | 18.57 | <0.0001 | 7.06 | 2.90 to 17.18 |
| BMI ≥ 30 Metab− |
1.85 | 0.73 | 6.38 | 0.011 | 6.34 | 1.51 to 26.56 |
| BMI ≥ 30 Metab+ |
2.20 | 0.46 | 23.13 | <0.0001 | 9.00 | 3.67 to 22.04 |
The normal weight/metabolically healthy group was used as a reference. Data are adjusted for age, sex, smoking, LDL-cholesterol, serum creatinine, and uric acid. BMI indicates body mass index in kg/m2; Metab+, metabolically unhealthy; Metab−, metabolically healthy.