Table 3.
Multivariable Cox model for risk of major adverse cardiovascular events in the participants <70 years of age categorized according to BMI (2 categories) and metabolic status defined according to standard criteria (without including LDL-cholesterol) or including LDL-cholesterol.
| Group | Wald Chi2 | p-Value | Hazard Ratio |
95% Confidence Limit |
|---|---|---|---|---|
| BMI < 25 and metabolically unhealthy | ||||
| Without including LDL-CT | 18.14 | <0.0001 | 6.91 | 2.40 to 16.83 |
| Including LDL-CT | 7.17 | 0.007 | 4.77 | 1.52 to14.95 |
| BMI ≥ 25 and metabolically healthy | ||||
| Without including LDL-CT | 6.68 | 0.011 | 3.85 | 1.35 to 10.96 |
| Including LDL-CT | 0.07 | 0.79 | 0.73 | 0.08 to 7.04 |
| BMI ≥ 25 and metabolically unhealthy | ||||
| Without including LDL-CT | 19.01 | <0.0001 | 7.19 | 2.96 to 17.45 |
| Including LDL-CT | 8.11 | 0.004 | 5.25 | 1.58 to 16.44 |
The normal weight/metabolically healthy group was used as a reference. Data are adjusted for age, sex, smoking, serum creatinine, and uric acid. BMI indicates body mass index in kg/m2; LDL-CT, LDL-cholesterol.