Expression of TMEM176B in lung cancer and clinical outcomes. (A) Tissue array IHC staining (400×, scale bar = 20 μm). The relative intensity of IHC staining was analysed using ImageJ software for comparisons with (B) tumour and adjacent normal tissues, (C) different tumour stages and (D) patients who survived or died from the disease. (E) TMEM176B expression in LUAD and LUSC (http://gepia2.cancer-pku.cn, accessed on 3 December 2023). Overall survival of TMEM176B in (F) NSCLC, (G) LUAD and (H) LUSC (https://kmplot.com/analysis/, accessed on 4 December 2023). **, p < 0.01, ***, p < 0.001 and ****, p < 0.0001.