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. 2024 Jul 3;16(13):2447. doi: 10.3390/cancers16132447

Figure 6.

Figure 6

Overexpression of TMEM176B-enhanced cell functions in lung adenocarcinoma through FGFR and JNK. Cell function assays for PC9 and A549 treated with FGFR, JNK, ERK, p38, AKT or PI3K inhibitors; cell proliferation (A), cell invasion (B), cell migration (C) and cell adhesion (D). A decreasing trend was observed for all cell functions using FGFR inhibitors; there was also a significant reduction in cell functions when cells were treated with the JNK inhibitor. *, p < 0.05, **, p < 0.01, ***, p < 0.001 and ****, p < 0.0001.