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. 2024 Jul 5;16(13):2464. doi: 10.3390/cancers16132464

Figure 6.

Figure 6

qPCR analysis of selected miRNA expression in CRC patients‘ samples, in comparison to healthy donors. The expression of seven selected miRNAs in tumor samples obtained from CRC patients (A). miR-182-5p, miR-196-5p, miR-425-5p and miR-429 expression in EVs isolated from patients’ plasma (B). The analysis was performed in CRC patients (n = 9) and healthy donors (n = 9). miRNA expression was analyzed using RT-qPCR and normalized to U6 expression using the 2−ΔΔCT method. Data were analyzed using the Kruskal–Wallis test with Dunn’s post-hoc test (A) or Mann–Whitney test (B), and medians ± IQR are shown. Asterisks mark significant differences: * p < 0.05, ** p < 0.01.