Fig. 5. Binding mode of compound 18h (grey sticks) within hEGFR (green cartoon PDB ID 1M17). In panel (A), the R-enantiomer is reported, and in panel (B), the S-enantiomer of the compound is reported. Residues in the binding sites are represented by thin sticks, and hydrogen bonds are shown as grey dotted lines. Images were generated using Maestro (Schrödinger, LLC, New York, 2020).
