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. 2024 Jul 12;14(31):22132–22146. doi: 10.1039/d4ra03902e

Effect of compounds 18c, 18g, and 18h and DMSO on Bax, Bcl-2, and caspases-3/-9 levels inside MDA-MB-231 cells treated with the compounds at their IC50 concentrations.

Gene expression (fold change)
Compound no. Casp3 Casp9 Bax Bcl2
18c 7.453 5.158 4.413 0.184
18g 3.945 4.386 3.054 0.252
18h 5.559 2.799 2.154 0.423
Staurosporine 7.594 5.456 6.104 0.249
Control 1 1 1 1