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. 2024 Jun 25;25(13):6929. doi: 10.3390/ijms25136929

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© 2024 by the authors.

Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).

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(A) mRNA expression levels of all the components of the splicing machinery analyzed in OSCC samples compared with non-tumoral adjacent tissue. (B) Individual description of mRNA expression levels of the statistically significant dysregulated spliceosome components in OSCC compared with non-tumoral adjacent tissue. Data are represented as mRNA levels normalized by a normalization factor (NF), calculated with the expression levels of three housekeeping genes: [actin-beta, (ACTB), hypoxanthine-guanine phosphoribosyltransferase 1 (HPRT), and glyceraldehyde 3-phosphate (GAPDH). Asterisks indicate significant differences (*, p < 0.05; **, p < 0.01; ***, p < 0.001; ****, p < 0.0001).