Table 5.

Mitochondrial changes in skeletal muscle in a mouse cachexia model.

	C	NT	CX	p
LetM1 (pg/g)	28 ± 0.2	28 ± 0.5	21 ± 0.4	<0.0001
PINK1 (pg/g)	6 ± 0.4	47 ± 0.7	39 ± 0.9	<0.0001
Parkin (pg/g)	8 ± 0.9	99 ± 1.5	76 ± 2.0	<0.0001
pCr (pg/g)	31 ± 0.2	31 ± 0.4	20 ± 0.6	<0.0001
C-I (pg/g)	9 ± 0.03	9 ± 0.06	5.8 ± 0.2	<0.0001

Changes in QCM aging markers were examined using a cachexia model in BALB/c mice, in which syngeneic CT26 mouse colon cancer cells were inoculated into the peritoneal cavity. Statistical differences (among three groups) were calculated by ordinal analysis of variance (ANOVA) with Bonferroni correction. LetM1: leucine zipper/EF-hand-containing transmembrane protein 1; PINK1: PTEN-induced putative kinase 1; pCr: phosphocreatine; C-I: complex I.