Figure 5.
Revoking the Protective Effects of SNX3 Deletion on Cardiomyocyte Viability through Ferroptosis Reactivation. A. Cell viability was determined by CCK-8 assay. B. ELISA kit was used to measure the LDH content in the medium to evaluate the cell viability. C-D. qPCR assay was used to determine the transcription of caspase-12 and Chop in cardiomyocytes. E. Mitochondrial membrane potential was observed through JC-1 probe. F. ATP production was determined by ELISA. *p<0.05 vs. PBS+WT-cell group, #p<0.05 vs. Dox+WT-cell group, ##p<0.05 vs. Dox+SNX3Cko-cell group.