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. 2024 Jun 27;25(13):7017. doi: 10.3390/ijms25137017

Table 1.

Articles/research discussed in the review.

Paper Year Species Source/Object Main Findings and Effects
Liu [1] 2013 human testis, sperm
Martins [2] 2013 sheep seminal plasma
Aslam [3] 2019 buffalo sperm TPPP2 is overexpressed 2.2x in low fertility sperm
Zhu [8] 2019 human, mice sperm, testis, epididymis sperm counts and motility of KO mice are lower; inhibition of TPPP2 decreased in vitro fertilization rate; mitochondrial dysfunction
Gódia [6] 2020 swine sperm high positive correlation between TPPP2 and curvilinear velocity of sperms; TPPP2 is the 5th most abundant mRNA in sperm
Wang [9] 2021 mice testis, sperm TPPP2 is downregulated in CFAP65 KO mice
Zhang [4] 2022 yak sperm upregulated in frozen-thawed high motility sperms
Alagundagi [7] 2023 human testis TPPP2 is upregulated 10x in NOA patients
Gacem [5] 2023 bull sperm TPPP2 is upregulated in high fertility bulls
Xu [10] 2023 human testis, tumors TPPP2 is prognostic indicator of tumor (hepatocarcinoma)