Table 2.

Expression of miR-137 in tissues of neurodegenerative disease patients.

Disease	Tissue	Expression Change 1
Alzheimer’s disease	frontal cortex [37]	downregulated
	dorsolateral prefrontal cortex [38]	NC
	parietal lobe [39]	NC
	inferior frontal gyrus [41]	NC
	superior temporal gyrus [40,41]	NC
	middle temporal gyrus [40]	NC
	anterior temporal cortex [42]	NC
	cerebellum [42]	NC
	whole blood [47]	NC
	plasma [46]	NC
	serum [43,44]	downregulated
	serum [45]	NC
Parkinson’s disease	prefrontal cortex [66]	downregulated (<72.5 years), NC (>72.5 years)
	substantia nigra [67]	NC
	amygdala [68]	NC
	plasma [69]	upregulated/NC
	plasma [70]	upregulated
Huntington’s disease	prefrontal cortex [79]	NC
	frontal cortex [80]	NC
	dorsal caudal striatum [80]	downregulated
Amyotrophic lateral sclerosis	spinal cord [90]	NC
	motor cortex [91]	NC
	skeletal muscle [102]	NC
	leukocytes [92,93]	NC
	whole blood [94,95]	NC
	plasma [98,101]	NC
	serum [96,97,99,100,103]	NC
Multiple sclerosis	white matter [105,106]	NC
	serum [107]	upregulated
	serum [108]	downregulated

¹ NC: no change compared to healthy control.