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. 2024 Jun 22;25(13):6857. doi: 10.3390/ijms25136857

Table 5.

Associations between disgust sensitivity measured via the DS-R and predictors evaluated via an OPLS model and multiple regression in the third trimester of pregnancy.

OPLS
(Predictive Component)
Multiple
Regression
Variable Variable Importance t-Statistics Component Loading t-Statistics R a Regression Coefficient t-Statistics
DS-R, Overall score
7α-Hydroxy-DHEA 0.757 1.96 * 0.390 8.96 0.626 ** 0.091 2.18 *
Androstenediol 0.856 3.01 ** 0.356 6.13 0.572 ** 0.152 2.69 *
5β-Androstane-3α,17β-diol 1.213 8.34 ** 0.401 12.35 0.641 ** 0.164 2.37 *
Cortisol 0.961 4.38 ** 0.364 7.18 0.584 ** 0.137 3.89 **
DS-R, Overall score, trimester 3 1.000 4.30 0.415 **
Explained variability 11.7% (8.8% after cross-validation)
DS-R, Core disgust
Pregnenolone 0.785 2.65 * 0.202 4.88 0.419 ** 0.041 1.85
17-Hydroxypregnenolone 1.361 4.82 ** 0.377 10.59 0.782 ** 0.071 5.51 **
DHEA 0.924 3.14 ** 0.386 9.49 0.801 ** 0.048 2.66 *
7α-Hydroxy-DHEA 1.153 5.17 ** 0.407 16.53 0.844 ** 0.060 3.29 **
7β-Hydroxy-DHEA 1.030 4.15 ** 0.374 10.36 0.775 ** 0.054 2.56 *
Androstenediol 1.125 5.00 ** 0.275 8.36 0.569 ** 0.059 3.68 **
5-Androstene-3 β,7α,17β-triol 0.984 2.89 * 0.336 11.14 0.696 ** 0.051 1.97 *
5α-Dihydrotestosterone 0.566 2.21 * 0.210 6.00 0.434 ** 0.029 2.20 *
Epiandrosterone 1.053 3.40 ** 0.345 6.85 0.716 ** 0.055 6.77 **
5α-Androstane-3β,17β-diol 0.792 2.45 * 0.200 5.18 0.415 ** 0.041 1.76
DS-R, Core disgust, trimester 3 1.000 3.01 0.342 **
Explained variability 11.7% (8.8% after cross-validation)
DS-R, Contamination disgust
Pregnenolone 0.690 3.19 ** 0.158 2.33 0.222 * 0.105 2.24 *
Testosterone 1.048 4.14 ** −0.376 −5.44 −0.546 ** −0.151 −4.06 **
Estradiol sulfate 0.950 2.59 * −0.269 −2.70 −0.393 * −0.158 −2.06 *
Estriol sulfate 0.636 2.53 * −0.167 −1.85 −0.255 −0.134 −2.69 *
Conjugated pregnanolone 1.032 5.42 ** 0.318 6.55 0.445 ** 0.035 0.90
Conjugated epipregnanolone 1.026 2.79 * 0.310 2.92 0.431 * 0.052 1.08
Conjugated 5α,20α-tetrahydroprogesterone 1.140 5.96 ** 0.301 4.73 0.410 ** 0.095 3.07 **
Conjugated 5α-pregnane-3α,20α-diol 1.131 3.01 ** 0.270 3.00 0.368 ** 0.103 1.32
Conjugated 5β,20α-tetrahydroprogesterone 0.978 2.60 * 0.265 2.62 0.362 * 0.080 0.95
Conjugated 5β-pregnane-3β,20α-diol 0.877 4.29 ** 0.282 3.94 0.386 ** 0.025 0.73
Maternal age 1.357 3.74 ** 0.390 3.65 0.569 ** 0.237 3.60 **
Multipara (1: yes/0: no) 0.925 3.14 ** 0.292 2.89 0.428 * 0.185 5.37 **
DS-R, Contamination disgust, trimester 3 1.000 13.56 0.570 **
Explained variability 32.5% (23.1% after cross-validation)
DS-R, Animal reminder disgust
Epiandrosterone 1.080 4.83 ** 0.532 7.50 0.676 ** 0.135 4.59 **
5α-Androstane-3β,17β-diol 0.894 2.93 * 0.505 6.19 0.641 ** 0.112 2.34 *
5β-Androstane-3α,17β-diol 0.951 4.60 ** 0.477 7.10 0.605 ** 0.119 3.54 **
Conjugated 5β-androstane-3α,17β-diol 1.063 2.98 * 0.489 3.08 0.613 ** 0.133 2.50 *
DS-R, Animal reminder disgust, trimester 3 1.000 2.09 0.317 *
Explained variability 10% (7.8% after cross-validation)

a R. Component loadings expressed as correlation coefficients with predictive component, * p < 0.05, ** p < 0.01.