Figure 6.
OFI-EVs speed up angiogenesis and wound healing process. (A,B). Wound closure representative images (0 and 24 h) after treatment with H2O2 alone or with OFI-EVs and relative quantitative analysis. Scale bars are 50 µm. (n = 3). (C) Optical images of HUVEC tubes at 4 h of incubation time of CTL (positive control treated with VEGF 20 ng/mL) and OFI-EVs; the image magnification was 20×. (D) Tube quantification with Image J software Version 1.54j Angiogenesis analyzer. *** p < 0.005 OFI-EVs vs. H2O2, ### p < 0.005 OFI-EVs vs. CTL. Data are expressed as means of three independent experiments ± S.D (n = 3).