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. 2024 Jun 26;25(13):6966. doi: 10.3390/ijms25136966

Table 10.

Gold-catalyzed intramolecular alkynol cyclization/hydroindolylation.

Reaction Scheme R1 R2 Compound Yield (%)
graphic file with name ijms-25-06966-i020.jpg 5-OMe H 59a 74
5-Me H 59b 80
5-F H 59c 86
5-Cl H 59d 66
5-Br H 59e 73
5-I H 59f 77
6-F H 59g 90
6-Cl H 59h 90
6-Br H 59i 76
4-Br H 59j 59
7-Me H 59k 76
H 2-Me 59l 75