Table 5.
Subgroup analysis of patients with adenomyosis stratified by day of embryo transfer and atosiban administration
| Day 3 embryo transfer (n = 212) | Day 5 embryo transfer (n = 124) | |||||
|---|---|---|---|---|---|---|
| Parameters |
Atosiban (n = 101) |
Control (n = 111) |
p value |
Atosiban (n = 67) |
Control (n = 57) |
p value |
| Age (years) | 39.4 ± 3.6 | 38.5 ± 3.8 | 0.074 | 35.7 ± 4.1 | 37.7 ± 3.7 | 0.007 |
| Body mass index (kg/m2) | 23.5 ± 4.1 | 23.5 ± 4.2 | 0.993 | 23.9 ± 3.6 | 24.0 ± 4.6 | 0.866 |
| Infertility duration (years) | 5.2 ± 3.6 | 5.3 ± 3.5 | 0.914 | 4.0 ± 2.5 | 5.5 ± 4.1 | 0.018 |
| Previous IVF attempts (n) | 3.3 ± 2.7 | 3.4 ± 2.5 | 0.663 | 2.3 ± 1.9 | 2.6 ± 1.9 | 0.332 |
| Primary infertility (%) | 50.5%(51/101) | 55.0%(61/111) | 0.516 | 41.8%(28/67) | 33.3%(19/57) | 0.333 |
| FSH (IU/L) | 5.5 ± 2.9 | 5.1 ± 2.9 | 0.279 | 5.5 ± 3.0 | 5.1 ± 2.8 | 0.393 |
| Anti-Müllerian hormone (ng/ml) | 2.25 ± 2.54 | 2.66 ± 2.44 | 0.230 | 5.03 ± 4.00 | 4.77 ± 3.15 | 0.687 |
| Endometrial thickness (mm) | 11.4 ± 2.1 | 11.8 ± 2.3 | 0.164 | 12.0 ± 2.5 | 11.2 ± 1.8 | 0.035 |
| At least one top-quality embryos transferred (%) | 84.2%(85/101) | 84.7%(94/111) | 0.916 | 71.6%(48/67) | 66.7%(38/57) | 0.549 |
| Biochemical pregnancy rate (%) | 52.5%(53/101) | 41.4%(46/111) | 0.108 | 68.7%(46/67) | 61.4%(35/57) | 0.398 |
| Clinical pregnancy rate (%) | 45.5%(46/101) | 39.6%(44/111) | 0.385 | 59.7%(40/67) | 61.4%(35/57) | 0.847 |
| Ongoing pregnancy rate (%) | 43.6%(44/101) | 27.0%(30/111) | 0.012 | 52.2%(35/67) | 56.1%(32/57) | 0.664 |
| Live birth rate (%) | 39.6%(40/101) | 25.2%(28/111) | 0.025 | 50.7%(34/67) | 54.4%(31/57) | 0.686 |
| Miscarriage rate (%) | 13.0%(6/46) | 36.4%(16/44) | 0.010 | 15.0%(6/40) | 10.0%(4/35) | 0.650 |
| Early miscarriage rate (%) | 4.3%(2/46) | 31.8%(14/44) | 0.001 | 12.5%(5/40) | 8.6%(3/35) | 0.582 |
| Late miscarriage rate (%) | 8.7%(4/46) | 4.5%(2/44) | 0.430 | 2.5%(1/40) | 2.9%(1/35) | 0.924 |
Data are presented as the mean ± standard deviation and % (n)
IVF, in vitro fertilization; FSH, follicular stimulating hormone