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. 2024 Jul 12;22:412. doi: 10.1186/s12951-024-02683-2

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© The Author(s) 2024

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated in a credit line to the data.

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Fig. 3 — Biocompatibility and rescue ability of GSH-CDs. (a) Immunofluorescence staining of Aggrecan. (Scale bar = 200 μm). (b) Toluidine blue staining (Scale bar = 200 μm). (c) Cell viability of NPCs incubated with different concentrations of GSH-CDs. (d) Cell viability of NPCs incubated with different concentrations of H₂O₂. (e) The protective effect of GSH-CDs against H₂O₂-induced oxidative stress in NPCs. Calcein/PI staining (f) of NPCs cocultured with GSH-CDs and H₂O₂ and semiquantitative analysis (g) of the different groups. (* indicates p value < 0.05, ** indicates p value < 0.01, **** indicates p value < 0.0001)