Table 2.

Comparison of imaging and laboratory measurements between Nigella sativa and Medroxyprogesterone groups

Variable		Nigella sativa Mean (SD)	Medroxyprogesterone Mean (SD)	Treatment	Time	Time* Treatment
Right ovarian volume (cc)	Before	11.96 (2.94)	11.95 (2.34)	< 0.770	0.213	0.002*
	After	9.40 (2.12)	11.17 (2.09)
Left ovarian volume (cc)	Before	11.28 (3.67)	11.91 (3.07)	0.316	0.343	0.010*
	After	8.36 (2.68)	10.84 (3.29)
Endometrial thickness (cm)	Before	10.24 (3.15)	9.01 (1.48)	< 0.001*	0.317	0.002*
	After	7.30 (2.04)	7.78 (1.55)
DHEA (ng/dL)	Before	123.74 (36.49)	125.02 (29.07)	0.736	0.232	0.074
	After	113.91 (28.11)	126.44 (28.88)
DHEA-S (ng/dL)	Before	128.79 (39.65)	133.98 (35.44)	0.628	0.559	0.120
	After	113.89 (31.10)	131.96 (34.28)
Testosterone (ng/dL)	Before	0.56 (0.49)	0.66 (0.67)	0.369	0.040*	0.001*
	After	0.33 (0.27)	0.65 (0.69)
Hirsutism severity score	Before	3.98 (1.56)	3.75 (1.40)	0.111	0.001*	< 0.001*
	After	1.36 (0.85)	3.38 (1.79)
LH (mU/dL)	Before	15.72 (3.19)	14.29 (3.40)	0.013*	0.004*	< 0.001*
	After	9.90 (2.06)	13.57 (2.87)
BMI (kg/m 2 )	Before	25.56 (3.63)	23.84 (2.61)	< 0.001*	0.517	0.252
	After	24.57 (2.36)	23.72 (2.47)
WHR	Before	0.92 (0.06)	0.89 (0.06)	0.064	0.768	0.814
	After	0.92 (0.07)	0.90 (0.07)
SBP (mmHg)	Before	105.10 (5.67)	103.30 (5.37)	0.035*	0.700	0.610
	After	105.04 (4.69)	103.28 (4.24)
DBP (mmHg)	Before	71.10 (2.73)	71.51 (2.87)	0.548	0.433	0.330
	After	71.66 (2.27)	71.55 (2.51)

DHEA: dehydroepiandrosterone, DHEA-S: dehydroepiandrosterone sulfate, LH: Luteinizing Hormone, BMI: Body Mass Index, WHR: Waist-hip ratio, SBP: Systolic Blood Pressure, DBP: Diastolic Blood Pressure

The repeated measures analysis of variance was used for the analysis

* Significant effect