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Cyclo(l-Pro-l-Tyr) isolated from culture broth inhibits tyrosinase activity. Tyrosinase activity was evaluated by measuring absorbance at 492 nm. Cyclo(l-Pro-l-Tyr): tyrosinase treated with 1 mg/mL purified cyclo(l-Pro-l-Tyr); control: tyrosinase treated with phosphate-buffered saline (PBS) (negative control); HA: tyrosinase treated with 2 mM homogentisic acid (positive control); bars: standard deviation (SD), *** p < 0.001.
