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Commercially available cyclo(l-Pro-l-Tyr) inhibits tyrosinase activity in a concentration-dependent manner. Tyrosinase activity was evaluated by measuring absorbance at 492 nm. Control: tyrosinase treated with phosphate-buffered saline (PBS) (negative control); HA: tyrosinase treated with 2 mM homogentisic acid (positive control); bars: standard deviation (SD), ** p < 0.01, *** p < 0.001.
