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Caspase-3 activation. Effect of increasing concentrations of Les-45 and Les-247 (1 nM–100 μM) on caspase-3 activity in the A549 (A,B) and BJ (C,D) cell lines after the 24- and 48-h exposures. Data are expressed as a mean (n = 6) with standard deviation. Statistically significant values determined by Tukey’s test for each study group. * p < 0.05, ** p < 0.01, *** p < 0.001, compared with control cells.
