Figure 6.

Correlations between patient values for serum MMA and plasma tHYC and gastric acid control (A,C) values after antisecretory drug intake (pH and acid hourly output after drug intake). Each solid circle or triangle is a value from one patient determined from the same NIH admission. During this admission, the post-drug acid output was determined for the hour prior to the next drug dose, and both the pH (A,C) and the acid output (B,D) were in mEq/h were determined and used in the correlations. The correlation coefficient, its significance, and the best-fitted regression line equation for each correlation are shown. The results show highly significant correlations with the increasing serum MMA or plasma tHCY, correlating directly with increased pH (decreasing acidity) of the gastric acid control value (A,C) and inversely with the acid output value in mEq/h (B,D).