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. 2024 Jun 30;25(13):7246. doi: 10.3390/ijms25137246

Figure 2.

Figure 2

Inhibition of RhoA with C3 reduces Cx43 GJCs activity but does not affect the functional state of Cx26 GJCs. HeLa cells transfected with Cx43 (a) or Cx26 (b) were exposed to C3 for 0.5, 1, 2, and 3 h. Phase contrast ((a,b) upper panels) and diffusion of LY ((a,b) bottom panels) in HeLa-Cx43 and HeLa-Cx26 are shown. Graphs show the dye coupling index in HeLa cells transfected with Cx43 (c) and Cx26 (d). Data are presented as mean ± SEM (n = 5; 20 cells for each condition); * p < 0.05. Scale bar: 30 µm.