. 2024 Jul 7;13(13):3969. doi: 10.3390/jcm13133969

Table 5.

Prognostic value of age, presence of IHD, and specific laboratory characteristics at admission for predicting postoperative outcome in patients with hip fracture.

Postoperative Myocardial Injury
Variable	¹ Total Cohort (n = 1273)		² IHD (n = 361)		³ IHD > 80 Years of Age (n = 277)
Variable	OR (95% CI)	p Value	OR (95% CI)	p Value	OR (95% CI)	p Value
Age > 80 years	3.84 (2.83–4.99)	<0.001	3.95 (2.92–5.27)	<0.001	NA	NA
IHD	2.30 (1.81–3.01)	<0.001	NA	NA	8.3 (5.58–12.36)	<0.001
LMR < 1.1	1.56 (1.18–2.06)	0.002	3.84 (2.44–6.05)	<0.001	16.08 (8.54–30.29)	<0.001
PLR > 280.0	1.44 (1.09–1.90)	0.01	3.87 (2.38–6.29)	<0.001	16.36 (8.44–11.74)	<0.001
Anaemia	1.08 (0.84–1.38)	0.568	3.37 (2.31–4.93)	<0.001	14.13 (8.06–24.78)	<0.001
Mon/Eos > 13.0	1.30 (1.01–1.66)	0.038	2.50 (1.70–3.68)	<0.001	13.43 (6.81–26.49)	<0.001
NLR > 7.5	1.40 (1.10–1.79)	0.006	3.47 (2.40–5.02)	<0.001	12.42 (7.03–21.94)	<0.001
Eos < 0.5 × 10⁹/L	1.38 (1.08–1.77)	0.01	2.77 (1.85–4.14)	<0.001	12.29 (6.44–23.47)	<0.001
SIRI > 5.1	1.42 (1.11–1.81)	0.005	3.44 (2.40–5.00)	<0.001	11.99 (6.81–21.09)	<0.001
Neutr/Alb × 10 > 2.4	1.25 (0.98–1.60)	0.068	3.22 (2.22–4.65)	<0.001	11.74 (6.60–20.88)	<0.001
Lymp < 1.2 × 10⁹/L	1.26 (0.99–1.62)	0.065	3.14 (2.20–4.48)	<0.001	11.69 (6.57–20.79)	<0.001
Monocytes > 1 × 10⁹/L	1.33 (0.96–1.85)	0.089	2.93 (1.73–5.00)	<0.001	11.61 (5.72–23.56)	<0.001
GGT/Lymp > 25.4	0.95 (0.74–1.21)	0.658	2.32 (1.63–3.30)	<0.001	11.17 (6.23–20.05)	<0.001
SII > 1650	1.41 (1.10–1.801)	0.006	3.33 (2.41–5.16)	<0.001	10.51 (5.96–18.53)	<0.001
Alb/RDW < 2.6	1.09(0.85–1.39)	0.493	2.94 (2.07–4.17)	<0.001	10.20 (6.01–17.33)	<0.001
RDW/Plt × 100 > 6.6	1.06 (0.83–1.36)	0.642	2.50 (1.78–3.51	<0.001	9.93 (5.74–17.17)	<0.001
Plt/ALT > 13.8	0.96 (0.75–1.23)	0.750	2.69 (1.85–3.91)	<0.001	9.87 (5.65–12.27)	<0.001
Neutr > 7.5 × 10⁹/L	1.21 (0.94–1.55)	0.139	2.82 (1.97-4.05)	<0.001	9.61 (5.26–17.58)	<0.001
RDW > 14.5%	1.17 (0.91–1.50)	0.227	2.84 (2.00–4.04)	<0.001	9.51 (5.73–15.79)	<0.001
Neutr/Mon > 12.1	1.10 (0.86–1.41)	0.434	2.37 (1.64–3.42)	<0.001	8.49 (4.74–15.21)	<0.001
ALT/Lymph < 14.6	1.28 (1.01–1.64)	0.045	2.06 (1.45–2.93)	<0.001	7.23 (4.21–12.40)	<0.001
Alb < 33 g/L	0.80 (0.59–1.09)	0.162	1.80 (1.07–3.02)	0.026	6.64 (3.37–13.08)	<0.001
Alb/Lymph/ < 25.4	0.96 (0.75–1.22)	0.728	2.10 (1.46–3.01)	<0.001	6.56 (3.64–11.85)	<0.001
Plt/Alb ratio > 5.9	0.89 (0.70–1.1)	0.351	2.12 (1.45–3.10)	<0.001	6.07 (3.50–10.53)	<0.001
Neutr/Eos > 156.3	1.38 (1.08–1.77)	0.01	2.05 (1.46–2.87)	<0.001	5.34 (3.27–8.74)	<0.001
Hb/Alb > 4.6	1.07 (0.84–1.37)	0.593	2.00 (1.39–2.88)	<0.001	6.03(3.34–10.89)	<0.001
Platelets > 400 × 10⁹/L	0.92 (0.46–1.89)	0.835	0.99 (0.23–4.15)	0.985	3.38 (0.73–15.62)	0.099
Hb/RDW < 8.8	0.91 (0.71–1.17)	0.465	1.64 (1.12–2.39)	0.011	4.98 (2.60–9.51)	<0.001
In-Hospital Death
Variable	¹ Total Cohort (n = 1273)		² IHD (n = 361)		³ IHD > 80 Years of Age (n = 277)
Variable	OR (95% CI)	p Value	OR (95% CI)	p Value	OR (95% CI)	p Value
Age > 80 years	4.90 (1.95–12.33)	0.001	5.04 (1.96–12.62)	<0.001	NA	NA
IHD	2.10 (1.24–3.51)	0.005	NA	NA	7.4 (2.55–21.51)	<0.001
LMR < 1.1	2.03 (1.18–3.49)	0.010	5.19 (2.65–10.15)	<0.001	28.67 (6.39–128.70)	<0.001
PLR > 280.0	2.16 (1.26–3.68)	0.005	5.58 (2.79–11.16)	<0.001	29.21 (6.49–131.42)	<0.001
Anaemia	1.35 (0.79–2.30)	0.270	3.39 (1.64–7.02)	0.001	13.24 (2.97–58.98)	0.001
Mon/Eos > 13.0	2.02 (1.17–3.48)	0.011	3.93 (1.86–8.30)	<0.001	10.99 (2.48–48.69)	<0.001
NLR > 7.5	1.72 (1.00–2.96)	0.051	3.62 (1.84–7.10)	<0.001	5.50 (2.01–15.07)	<0.001
Eos < 0.5 × 10⁹/L	2.44 (1.42–4.21)	0.001	4.76 (2.30–9.84)	<0.001	13.96 (3.16–61.61)	0.001
SIRI > 5.1	2.13 (1.23–3.67)	0.007	3.95 (2.03–7.66)	<0.001	6.18 (2.27–16.77)	<0.001
Neutr/Alb × 10 > 2.4	1.69 (1.00–2.88)	0.051	3.46 (1.72–6.98)	0.001	23.06(3.04–175.15)	0.002
Lymp < 1.2 × 10⁹/L	1.18 (0.68–2.03)	0.561	2.54 (1.27–5.08)	0.008	18.6 (2.46–140.86)	0.005
Monocytes > 1.0 × 10⁹/L	0.91 (0.44–1.89)	0.807	1.22 (0.36–4.12)	0.75	3.35 (0.54–20.56)	0.192
GGT/Lymp > 25.4	1.70 (1.00–2.89)	0.050	3.34 (1.66–6.72)	0.001	20.53 (2.70–156.06)	0.004
SII > 1650.0	2.33 (1.32–4.13)	0.004	4.63 (2.26–9.48)	<0.001	5.33 (1.95–14.63)	<0.001
Alb/RDW < 2.6	2.71 (1.53–4.79)	0.001	2.23 (1.25–3.98)	0.007	5.42 (2.41–12.19)	<0.001
RDW/Plt × 100 > 6.6	1.04 (0.61–1.78)	0.882	2.13 (1.04–4.35)	0.038	5.23 (1.47–18.57)	0.005
Plt/ALT > 13.8	1.24 (0.73–2.08)	0.424	2.61 (1.34–5.11)	0.005	4.87 (1.75–13.57)	0.001
Neutrophils > 7.5 × 10⁹/L	1.39 (0.80–2.43)	0.240	2.80 (1.36–5.75)	0.005	14.83 (1.96–112.48)	0.009
RDW > 14.5%	1.86 (1.09–3.16)	0.022	3.93 (1.98–7.79)	<0.001	12.10 (3.64–70.42)	<0.001
Neut/Mon > 12.1	1.68 (0.98–2.87)	0.057	3.39 (1.67–6.89)	0.001	9.94 (2.26–43.72)	0.002
ALT/Lymph < 14.6	0.57 (0.33–0.97)	0.037	1.30 (0.61–2.76)	0.488	5.75 (1.24–26.69)	0.026
Alb < 33 g/L	1.23 (0.66–2.27)	0.512	3.33 (1.45–7.64)	0.004	15.17 (3.87–59.53)	<0.001
Alb × Lymph/ < 25.4	1.38 (0.81–2.38)	0.233	1.05 (0.43–2.35)	0.921	3.03 (0.62–14.88)	0.173
Plt/Alb ratio > 5.9	1.82 (1.05–3.16)	0.032	3.95 (1.83–8.55)	<0.001	4.36 (1.55–12.27)	0.003
Neutr/Eos > 156.3	2.49 (2.42–4.37)	0.001	3.13 (1.75–5.57)	<0.001	2.39 (0.61–9.43)	0.199
Hb/Alb > 4.6	1.81 (1.06–3.09)	0.030	1.13 (0.40–2.56)	0.768	3.63 (0.75–17.47)	0.108
Platelets > 400 × 10⁹/L	1.65 (0.49–3.51)	0.417	8.43 (1.64–43.38)	0.011	35.87 (4.87–263.95)	<0.001
Hb/RDW < 8.8	1.92 (1.08–3.40)	0.025	1.33 (0.53–3.34)	0.544	2.34 (0.46–11.88)	0.292

Abbreviations: As in Table 1, OR, odds ratio; CI, confidence interval; ¹ adjusted for age, gender and all clinical variables which were significantly associated with postoperative myocardial injury and/or hospital mortality on univariate analyses; ² comparison IHD patients with the rest of the cohort, adjusted for age (as a continues variable) and all clinical variables which were significantly associated with postoperative myocardial injury and/or hospital mortality on univariate analyses; ³ comparison IHD patients aged > 80 years and younger than 80 years with and without the analysed haematological characteristic. Significant p values are expressed in bold characters.