Table 1.
Cardio-metabolic features across tertiles of the TyG index in a cohort comprising both MetS and controls.
| Variable | Tertile 1 n = 34 |
Tertile 2 n = 34 |
Tertile 3 n = 34 |
p-Value * |
|---|---|---|---|---|
| Female/Male, n
(%) |
27/7 (79/21) |
27/7 (79/21) |
24/10 (71/29) |
0.39 |
| Control/MetS, n
(%) |
29/5 (85/15) |
11/23 (32/68) |
3/31 (9/91) |
<0.0001 |
| TyG index | 7.9 (7.7–8.2) | 8.5 (8.4–8.6) | 9.1 (8.9–9.3) | <0.0001 |
| Age (years) | 46 (41–56) | 53 (45–61) | 54 (48–60) | 0.03 |
| Waist (cm) | 87 (81–99) | 103 (95–117) | 107 (97–117) | <0.0001 |
| Weight (kg) | 80.5 (71.4–91.8) | 98.2 (84.1–111.4) | 92.7 (82.7–112.3) | 0.003 |
| BMI (kg/m2) | 29.0 (25.8–32.4) | 34.3 (31.9–41.0) | 33.8 (28.5–39.2) | 0.002 |
| Systolic BP (mmHg) | 120 (108–132) | 132 (116–139) | 129 (122–136) | 0.009 |
| Diastolic BP (mmHg) | 74 (66–82) | 80 (72–86) | 79 (75–86) | 0.007 |
| Glucose (mg/dL) | 88 (83–95) | 95 (88–102) | 100 (94–109) | <0.0001 |
| Insulin (mU/L) | 6.0 (3.8–10.2) | 10.6 (7.2–17.1) | 13.0 (9.4–21.1) | <0.0001 |
| Total cholesterol (mg/dL) | 177 (159–198) | 198 (183–213) | 208 (188–224) | 0.0008 |
| HDL cholesterol (mg/dL) | 54 (43–64) | 47 (35–50) | 35 (31–41) | <0.0001 |
| Non-HDL cholesterol (mg/dL) | 122 (108–147) | 154 (136–161) | 159 (152–181) | <0.0001 |
| Triglycerides (mg/dL) | 62 (50–70) | 107 (97–122) | 174 (156–211) | <0.0001 |
| hsCRP (mg/L) | 1.1 (0.4–4.0) | 3.4 (1.3–5.4) | 2.6 (1.7–4.6) | 0.006 |
| HOMA-IR | 1.4 (0.8–2.3) | 2.6 (1.6–3.7) | 3.5 (2.2–5.7) | <0.0001 |
| FFA (umol/L) | 320 (180–440) | 580 (400–760) | (780(670–950) | 0.0001 |
| Adipo-IR (mmol/pmol) | 11 (6–36) | 42 (27–69) | 91 (55–106) | <0.0001 |
* The Jonckheere–Terpstra Test for trend for continuous variables and the Cochran–Armitage test for categorical variables. Adipo-IR—adipose tissue insulin resistance; FFA—free fatty acids. The results are reported as median values (25th–75th percentile).