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(A) Docking-predicted pose of PIP2 (represented in spheres) bound to a model of Kv7.3 tetramer (the single PIP2-bound subunit is represented in wheat cartoon, the other subunits in gray) with the presence of calmodulin (CaM) molecule (represented as light blue cartoon). (B) Details of PIP2 docking pose into a Kv7.3 subunit. The residues involved in PIP2/Kv7.3 interactions are represented as thin sticks. H-bonds are represented by yellow dashed lines.
