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The most active compounds docked in the binding site of BRAF PDB:4XV2. (A) Three-dimensional interaction of compound 4a (Yellow), 4f (Green), 4r (Red), sorafenib (Cyan), and dabrafenib (Magentas) with the binding site of BRAF (B) Two-dimensional presentation of the interaction of compound 4a. (C) Two-dimensional presentation of the interaction of compound 4f. (D) Two-dimensional presentation of the interaction of compound 4r.
