FIG. 1.

Schematic summary of the AB, BC, and CD fragments of VP6 and synthetic peptides (1 through 11 and 6-14) used to map protective domains and epitopes in VP6 and in its CD region. The numbers in front of and following the bars indicate the locations of the regions in the primary sequence of VP6. The protective efficacies of VP6 and the two groups of VP6 fragments (i.e., AB, BC, and CD and CD1, CD2, CD3, and CD4) and synthetic peptides are indicated as percent reduction in rotavirus shedding relative to mock-immunized mice. ^a Average percent reduction in shedding (range) of three experiments.