Table 3.
The results of hierarchical patient (dataset A) clustering based on 8 most discriminative predictors (the clusters are indicated as C1-C10).
| Parameter | C1 (n = 303) | C2 (n = 400) | C3 (n = 1) | C4 (n = 44) | C5 (n = 153) | C6 (n = 618) | C7 (n = 13) | C8 (n = 201) | C9 (n = 1) | C10 (n = 1) | P value |
|---|---|---|---|---|---|---|---|---|---|---|---|
| Age [years] | 52.99 ± 18.34 (54.00) | 57.36 ± 18.43 (61.00) | 67.00 ± 0.00 (67.00) | 56.09 ± 18.72 (55.00) | 64.13 ± 15.32 (67.00) | 62.52 ± 15.33 (64.00) | 70.62 ± 10.87 (72.00) | 57.03 ± 17.41 (59.00) | 44.00 ± 0.00 (44.00) | 81.00 ± 0.00 (81.00) | <.001 |
| Alanine aminotransaminase [U/L] | 20.83 ± 9.24 (19.30) | 29.11 ± 20.27 (22.80) | 909.00 ± 0.00 (909.00) | 180.48 ± 85.08 (164.00) | 30.56 ± 18.73 (25.40) | 29.44 ± 18.39 (24.05) | 27.72 ± 18.95 (23.90) | 29.12 ± 22.69 (21.70) | 546.80 ± 0.00 (546.80) | 2170.00 ± 0.00 (2170.00) | <.001 |
| Aspartate aminotransaminase [U/L] | 20.97 ± 8.32 (19.40) | 26.83 ± 16.62 (22.05) | 241.90 ± 0.00 (241.90) | 154.29 ± 82.17 (134.05) | 37.81 ± 26.48 (28.40) | 27.19 ± 14.35 (22.65) | 26.21 ± 20.36 (18.10) | 30.03 ± 23.44 (22.80) | 1340.00 ± 0.00 (1340.00) | 3023.00 ± 0.00 (3023.00) | <.001 |
| BMI [kg/m2] | 28.87 ± 6.66 (27.90) | 30.33 ± 7.04 (29.82) | 25.28 ± 0.00 (25.28) | 29.57 ± 5.87 (29.48) | 30.42 ± 6.39 (30.43) | 31.32 ± 6.75 (31.01) | 27.25 ± 4.98 (27.7) | 28.98 ± 7.22 (28.53) | 25.60 ± 0.00 (25.60) | 23.96 ± 0.00 (23.96) | <.001 |
| Hyperuricemia | 59 (19.47%) | 126 (31.50%) | 0 (0.00%) | 10 (22.73%) | 56 (36.60%) | 194 (31.39%) | 3 (23.08%) | 55 (27.36%) | 0 (0.00%) | 1 (100.00%) | .003 |
| Metformin | 129 (42.57%) | 193 (48.25%) | 0 (0.00%) | 5 (11.36%) | 64 (41.83%) | 362 (58.58%) | 6 (46.15%) | 81 (40.30%) | 0 (0.00%) | 0 (0.00%) | <.001 |
| Platelet count [109/L] | 249.61 ± 16.99 (252.00) | 298.84 ± 22.40 (299.00) | 156.00 ± 0.00 (156.00) | 189.30 ± 81.59 (186.50) | 115.01 ± 35.81 (128.00) | 197.76 ± 24.49 (197.00) | 716.54 ± 142.54 (683.00) | 395.65 ± 53.68 (385.00) | 66.00 ± 0.00 (66.00) | 113.00 ± 0.00 (113.00) | <.001 |
| Type of diabetes [% of type 1] | 119 (39.27%) | 100 (25.00%) | 0 (0.00%) | 3 (6.82%) | 13 (8.50%) | 85 (13.75%) | 1 (7.69%) | 48 (23.88%) | 1 (100.00%) | 0 (0.00%) | <.001 |
| MASLD | 117 (38.61%) | 188 (47.00%) | 1 (100.00%) | 40 (90.91%) | 140 (91.50%) | 416 (67.31%) | 3 (23.08%) | 84 (41.79%) | 1 (100.00%) | 1 (100.00%) | <.001 |
For each parameter (if applicable), mean ± SD is reported together with the median (in parentheses). For each binary parameter, we calculated the total number of ones and the percentage of ones. The P values were obtained using the Kruskal-Wallis test with post hoc Dunn. The row with the target (MASLD) is boldfaced.