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Pathogenicity of NSP4 aa112–175 given intraperitoneally to 6- to 7-day-old CD1 micea
| Dose (nmol) | No. of mice with diarrhea/total inoculated (%)
|
|
|---|---|---|
| NSP4 aa112–175 | Full-length NSP4 | |
| 0.2 | 3/11 (27) | 3/11 (27) |
| 1.0 | 4/11 (36) | 4/11 (36) |
| 5.0 | 4/10 (40) | NDb |
Additionally, 11 mice were inoculated with 50 μl of PBS alone; none of them developed diarrhea.
ND, not done.
