Figure - PMC

Skip to main content

An official website of the United States government

Here's how you know

Here's how you know

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS
A lock ( ) or https:// means you've safely connected to the .gov website. Share sensitive information only on official, secure websites.

View full-text article in PMC

[Preprint]. 2024 Jul 3:2024.07.03.601903. [Version 1] doi: 10.1101/2024.07.03.601903

Search in PMC
Search in PubMed
View in NLM Catalog
Add to search

This work is licensed under a Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International License, which allows reusers to copy and distribute the material in any medium or format in unadapted form only, for noncommercial purposes only, and only so long as attribution is given to the creator.

PMC Copyright notice

Figure 1: — (A) Schematic for TRADE analysis, starting from condition-wise gene expression counts and ending with estimated distribution of Log2FC. (B) Estimation of various simulated effect size distributions (Point-Normal with 95% Null, Point-Normal with 75% Null, Infinitesimal/normally distributed). Purple trace shows true effect size distribution; gray traces show estimated distributions across 100 replicates. (C) Comparison of estimated and true transcriptome-wide impact in simulations.