Table 1.
Baseline characteristics and number of cancer outcomes during follow-up in the total cohort and the full sibling cohort.
| Total cohort (N=1 124 049) | Full sibling cohort (N=477 453) | |
|---|---|---|
| Baseline data | ||
| Birth year, median (IQR) | 1966 (1960 to 1971) | 1965 (1961 to 1970) |
| Age at conscription, mean (SD) | 18.3 (0.7) | 18.3 (0.7) |
| Body mass index, kg/m 2 | ||
| Median (range) | 21.4 (15.0 to 59.2) | 21.3 (15.0 to 59.2) |
| Body mass index categories, n (%) | ||
| Underweight (<18.5 kg/m2) | 88 966 (7.9) | 37 884 (7.9) |
| Normal weight (18.5–24.9 kg/m2) | 913 586 (81.3) | 390 811 (81.9) |
| Overweight (25.0–29.9 kg/m2) | 102 267 (9.1) | 41 248 (8.6) |
| Obesity (>30.0 kg/m2) | 19 230 (1.7) | 7510 (1.6) |
| Cardiorespiratory fitness, Watt max | ||
| Median (range) | 271 (100 to 999) | 271 (100 to 999) |
| Watt max by quartiles, median (range) | ||
| Quartile 1 | 217 (100 to 236) | 217 (100 to 236) |
| Quartile 2 | 253 (237 to 270) | 253 (237 to 270) |
| Quartile 3 | 290 (271 to 312) | 290 (271 to 312) |
| Quartile 4 | 339 (313 to 999) | 339 (313 to 999) |
| Parental level of education, n (%) | ||
| Compulsory school <9 years | 319 242 (28.4) | 139 246 (29.1) |
| Secondary education | 505 510 (45.0) | 210 246 (44.0) |
| Post-secondary education <3 years | 123 757 (11.0) | 50 210 (10.5) |
| Post-secondary education >3 years | 175 540 (15.6) | 77 751 (16.3) |
| Parental highest income, n (%) | ||
| Category 1 (low income) | 55 055 (4.9) | 18 918 (4.0) |
| Category 2 | 108 836 (9.7) | 41 820 (8.8) |
| Category 3 | 237 953 (21.2) | 101 150 (21.2) |
| Category 4 | 338 444 (30.1) | 145 735 (30.5) |
| Category 5 (high income) | 383 761 (34.1) | 169 830 (35.6) |
| Number of cancer events (median age at event) during follow-up | ||
| Overall cancer diagnosis | 98 410 (55.1) | 41 293 (54.8) |
| Overall cancer mortality | 16 789 (55.7) | 6908 (55.3) |
| Head and neck | 4026 (54.1) | 1692 (53.7) |
| Oesophagus | 1178 (57.1) | 464 (57.0) |
| Lung | 3131 (57.4) | 1263 (57.1) |
| Stomach | 1430 (55.4) | 599 (55.3) |
| Pancreas | 2255 (57.2) | 943 (57.0) |
| Liver, bile ducts, and gallbladder | 2246 (57.1) | 925 (56.8) |
| Colon | 5320 (55.1) | 2177 (54.8) |
| Rectum | 3917 (55.7) | 1625 (55.6) |
| Kidney | 2741 (54.6) | 1151 (54.5) |
| Prostate | 24 225 (59.5) | 10 042 (59.1) |
| Bladder | 3490 (56.9) | 1432 (56.3) |
| Myeloma | 1460 (55.8) | 580 (55.9) |
| Melanoma skin | 10 026 (52.5) | 4216 (52.5) |
| Non-melanoma skin | 27 302 (54.5) | 11 509 (54.2) |
IQR = interquartile range. SD = standard deviation.