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(A) Oncoprint of the most common alterations (≥ 2% overall mutation rate), along with alterations present in the top 10 most frequently altered genes for any individual biopsy site. (B) Heatmap of mutation rates by metastatic site for genes shown in panel 2A. *P < 0.05. Abbreviations: CNS: central nervous system; GI, gastrointestinal; MiT, Microphthalmia transcription factor; pTERT, TERT promoter.
