Table 3. Metabolic Stability of ELQ-596 in the Presence of Liver Microsomes.
| test compound | species | T1/2 (min) | Clint (mL/min/kg) |
|---|---|---|---|
| ketanserin | mouse | 19.10 | 285.69 |
| rat | 14.41 | 172.38 | |
| human | 27.29 | 63.69 | |
| ELQ-596 | mouse | >4000 | 0 |
| rat | >4000 | 0 | |
| human | >4000 | 0 |
Official websites use .gov
A
.gov website belongs to an official
government organization in the United States.
Secure .gov websites use HTTPS
A lock (
) or https:// means you've safely
connected to the .gov website. Share sensitive
information only on official, secure websites.