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. 2022 Nov 11;55(4):1010–1019. doi: 10.1007/s10578-022-01461-1

Table 1.

Summary of patient’s treatment data

Patients Sex Age (yrs) Diagnosis age (yrs) ASDs
level
Comorbidities Medications Alternative intervention Pre-T (Hz) Post-T (Hz) Stimulation site Reported outcomes
1 M 3 1.5 3 ST - ABA 9 9.2 Pz Fpz Improved eye contact, independency, spatial awareness, sleep, vocalisation, physical activity, and mood
2 M 3 1.5 3 ST Melatonin SP, OT 9.5 9.8 Pz Fpz Improved sleep, speech articulation and expression, imitation, physical activity, confidence, eye contact, spatial awareness, cognition, and non-verbal communication. A case of hypersalivation and “tongue-twisting”.
3 M 3 3 2 - Iron and vitamin B - 8.7 9.1 Pz Fpz Improved anxiety, spatial awareness, listening skills, and vocalisation. Nil changes to eye contact.
4 M 3 2 3 ST Melatonin SP, OT and psychology 8.2 8.9 Pz Fpz Improved vocalisation, non-verbal communication, spatial awareness, tactile skills, social skills, sleep, eye contact, anxiety, behaviour (aggression)
5 M 4 2 2 ST - - 8.7 8.4 Pz Fpz Improved vocalisation, physical activity, eye contact, social skills, sleep, concentration, and anxiety. Nil changes in communication skills.
6 M 5 2 3 - - - 9.3 9.3 Pz Fpz Improved cognition, social skills, vocalisation, tactile skills, eye contact, and anxiety. Nil changes to diet diversity and speech articulation.
7 F 5 3 3 - - - 9.3 9.3 Pz Fpz Improved listening, handwriting, and spatial awareness. More tantrums and screaming (sensory overload).
8 M 5 3 3 ST Melatonin CBT and OT 10.1 10.2 Pz Fpz Improved curiosity and concentration, spatial awareness, and social skills. Nil changes to sleep and speech.
9 M 5 3 3 - Naturopath SP, OT and psychology 9.3 9.3 Pz Fpz Improved emotional regulation, eye contact, social skills, spatial awareness, and vocalisation.
10 M 5 3 3 ST Vitamin B Craniosacral stimulation 9.2 9.1 FPz More emotional (crying for no reason)
11 M 6 4 3 Seizure Cod liver oil, zinc, vitamin D, Iron - 9.1 10.4 Pz Fpz Improved anxiety, social skills, physical activity, vocalisation, imitation, behaviour, and concentration.
12 F 6 2.5 3 ST - - 8.8 9.1 Pz Fpz Improved sleep, mood, vocalisation, and physical activity. Nil changes to the intensity of emotion and anger outbursts.
13 M 6 6 2 ST Naturopath - 8 10.4 Pz Fpz Improved decision-making and mood. Increased screaming (due to more awareness or sensory overload)
14 M 6 3 2 ST, ADHD Methylphenidate, risperidone, clonidine, melatonin - 8.7 9.1 Pz Fpz Improved anxiety, verbal communication, emotional regulation, phobia, and social skills
15 M 6 3.5 2 - - SP, OT 9.8 10.3 Pz Fpz Improved speech, emotional regulation (anger), anxiety and behaviour.
16 M 6 3 3 ST Melatonin Nemechek protocol 9 8.8 Pz Fpz Improved mood, concentration, verbal and non-verbal expression, sleep, and diet diversity. Nil changes to physical activity.
17 M 7 1 3 ST, anxiety Melatonin, CBD, multivitamins - 8.5 8.2 Pz Fpz Improved social skills, cognition, self-expression, mood, and diet diversity.
18 M 7 4 3 ST, anxiety - SP, OT 10.4 9.8 Pz Fpz Improved anxiety, repetitive behaviour, and listening skills.
19 M 7 6 2 ST - - 9.1 9 Pz Fpz Improved sleep, diet diversity, anxiety, phobia. Nil changes to emotional dysregulation.
20 M 7 4 3 ST Methylphenidate - 8.7 9.5 Pz Fpz Improved social skills, behaviours (aggression and meltdown), sleep and vocalisation.
21 M 7.5 2 3 - Zinc, Magnesium - 9.3 9.3 Fpz Improved eye contact, vocalisation, mood, sleep, listening response, spatial awareness, and emotional regulation.
22 M 8 2.5 3 - - OT 10.3 10.3 Pz Fpz Improved anxiety, phobia, concentration, listening response, and verbal communication.
23 M 8 4 2 - - SP, OT 9.1 9.6 Pz Fpz Improved sleep, emotional regulation, and concentration.
24 M 8 7 1 ST, anxiety - SP, OT and psychology 8.7 8.7 Pz Fpz Improved social skills, emotional dysregulation and behaviour (aggression).
25 M 9 2 3 ST - SP, OT and sound 9.2 8.8 Fpz Improved spatial awareness, concentration, social skills, eye contact, listening response, physical activity, and behaviour.
26 M 9 5 3 ST - - 9.5 9.7 Pz Fpz Improved cognition, eye contact, and special awareness. Nil changes in sleep and verbal communication.
27 M 8 4 3 ADHD - SP, OT 10 9.9 Pz Fpz Improved mood, eye contact, verbal communication, and anxiety. Nil changes to physical activity.
28 M 9 1.5 2 - Methylphenidate SP, OT 9 9 Pz Fpz Improved communication, mood, and behaviour. Nil changes to listening response.

Key: Not listed (-); Applied behaviour analysis (ABA), Attention deficits hyperactive disorder (ADHD), Cannabidiol (CBD); Cognitive behavioural therapy (CBT), Occupational therapy (OT), posttraumatic stress disorder (PTSD), Sleep trouble (ST), and Speech therapy (SP): Pre-treatment (pre-T): Post-treatment (post-T)