Table 3.
Samples currently stored at the GHTO.
| Total Visits Blood Collection | Unique Participants Blood Collection | PBMC | CSF* | Plasma | |||||||
|---|---|---|---|---|---|---|---|---|---|---|---|
| DNA | RNA | DNA | RNA | All | Unique IDs | Cell Pellet | All | Unique IDs | All | Unique IDs | |
| AD | 2,821 | 686 | 1,648 | 423 | 94 | 88 | 28 | 519 | 401 | 2,809 | 1534 |
| ADAD | 42 | 7 | 16 | 3 | 1 | 1 | . | 14 | 5 | 31 | 11 |
| ADRD | 1,261 | 576 | 924 | 510 | 84 | 84 | 46 | 136 | 96 | 1,230 | 827 |
| Control | 5,275 | 1,700 | 2,045 | 849 | 494 | 434 | 178 | 1,425 | 725 | 4,087 | 1,622 |
| DLB | 58 | 22 | 40 | 20 | . | . | . | 4 | 4 | 59 | 40 |
| FTD | 176 | 31 | 114 | 23 | 2 | 2 | . | 12 | 9 | 83 | 54 |
| Total | 9,633 | 3,022 | 4,787 | 1,828 | 675 | 609 | 252 | 2,110 | 1,240 | 8,299 | 4,088 |
*Residual samples used to generate omic data obtained via tissue request. Knight-ADRC CSF biobanking is performed by the Fluid Biomarker Core.
PBMC = Peripheral Blood Mononuclear Cell; CSF = CerebroSpinal Fluid; DNA = DesoxyriboNucleic Acid; RNA = RiboNucleic Acid; AD = Alzheimer Disease; ADAD = Autosomal Dominant Alzheimer Disease; ADRD = Alzheimer Disease Related Dementia; DLB = Lewy Body Dementia; FTD = FrontoTemporal Dementia
Each sample type includes total samples and unique individual to account for the longitudinal biological sampling. Brain sample information can be found in Table 4.