Lee 2005.

Methods	Double‐blind, cross‐over RCT.
Participants	13 individuals with haemophilia (11 haemophilia A, 7 severe; 2 haemophilia B, both severe) undergoing dental scaling.
Interventions	Experimental treatment: placebo infusion (0.9% saline) within 1 hour prior to the dental procedure; 10 ml 5% tranexamic acid mouthwash up to four times per day for 8 days, according to visual check for gingival bleeding by the participant. Control treatment: factor concentrate infusion according to the type and severity of haemophilia; placebo mouthwash with the same instructions.
Outcomes	Post‐scaling haemorrhage (need for factor replacement treatment; reported gingival bleeding). Use of mouthwash (overall use; number of times used to control bleeding; number of times electively not used when bleeding occurred; number of times used despite no bleeding).
Notes	Published data did not enable to extract outcomes clearly. Additional information was requested to the authors.

RCT: randomised controlled trial