Table 6.

Correlation between CDKN1B expression in tumor tissues and clinical parameters of PCa patients

Clinical characteristics		n = 38		CDKN1B IHC score		p-value
				High (n = 20)	Low (n = 18)
Age (years)	≥ 66	17		8	9	0.5359
	< 66	21		12	9
PSA (ng/mL)	≥ 9.67	13		7	6	0.9139
	< 9.67	25		13	12
Gleason score	≤ 6	11		11	0	0.0007*
	3 + 4	10		7	3
	4 + 3	9		2	7
	≥ 8	8		0	8
AR status	Positive	30		16	14	0.8668
	Negative	8		4	4
p53 status	Positive	15		7	8	0.552
	Negative	23		13	10
T stage	pT2	23		17	6	0.0042*
	pT3	13		3	10
	pT4	2		0	2
Lymph node metastasis	Absent		27	17	10	0.0457*
	Present		11	3	8

Chi-square test was used to analyze the correlation between gene expression in PCa tumor tissues and clinical characteristics of patients. PCa: prostate cancer; PSA: prostate-specific antigen; AR: androgen receptor; IHC: immunohistochemistry; *p < 0.05