Table 1.
Distribution of baseline sample characteristics by dementia status after 6 years of follow-up, United States Health and Retirement Study, 2006 and 2008
| Characteristic | Overall Sample N = 6908a | Incident dementia N = 795a | Cognitively Normal or CIND N = 6113a | p valueb |
|---|---|---|---|---|
| Baseline CRP (μg/mL) | 4.37 (8.00) | 5.13 (11.28) | 4.27 (7.46) | 0.004 |
| Age (years) | 67.11 (9.91) | 75.64 (9.62) | 66.00 (9.40) | <0.001 |
| Race | <0.001 | |||
| Non-Hispanic Black | 813 (12%) | 171 (22%) | 642 (11%) | |
| Hispanic | 633 (9.2%) | 103 (13%) | 530 (8.7%) | |
| Non-Hispanic white | 5462 (79%) | 521 (66%) | 4941 (81%) | |
| Sex | 0.473 | |||
| Female | 4234 (61%) | 478 (60%) | 3756 (61%) | |
| Male | 2674 (39%) | 317 (40%) | 2357 (39%) | |
| Educational Category | <0.001 | |||
| > College | 676 (9.8%) | 25 (3.1%) | 651 (11%) | |
| College/Some | 1297 (19%) | 68 (8.6%) | 1229 (20%) | |
| HS or < | 4935 (71%) | 702 (88%) | 4233 (69%) | |
| Alcohol Use (# drinks/day when drinks) | 0.71 (1.30) | 0.40 (1.07) | 0.75 (1.32) | <0.001 |
| Smoking Status | 0.430 | |||
| Current | 851 (12%) | 104 (13%) | 747 (12%) | |
| Former | 2966 (43%) | 352 (44%) | 2614 (43%) | |
| Never | 3091 (45%) | 339 (43%) | 2752 (45%) | |
| Body Mass Index (kg/m2) | 28.50 (5.79) | 27.17 (5.38) | 28.68 (5.82) | <0.001 |
| Chronic Conditions | 1.88 (1.36) | 2.47 (1.51) | 1.80 (1.32) | <0.001 |
| APOE-ε4 | <0.001 | |||
| At least 1 copy | 1859 (27%) | 258 (32%) | 1601 (26%) | |
| No copy | 5049 (73%) | 537 (68%) | 4512 (74%) | |
| Time (years) | <0.001 | |||
| 2 | 302 (4.4%) | 302 (38%) | 0 (0%) | |
| 4 | 269 (3.9%) | 269 (34%) | 0 (0%) | |
| 6 | 6337 (92%) | 224 (28%) | 6113 (100%) | |
| Wave | <0.001 | |||
| 2006 | 3485 (50%) | 339 (43%) | 3146 (51%) | |
| 2008 | 3423 (50%) | 456 (57%) | 2967 (49%) |
CRP C-reactive protein, APOE-ε4 apolipoprotein E ε4 allele carrier status, CIND cognitive impairment non-dementia
aMean (SD); n (%)
bOne-way ANOVA; Pearson’s Chi-squared test