FIG. 5.

Infectious virus titers recovered from the eyes of HSV-1F-infected PKO and wild-type mice. Mice were infected as indicated in Materials and Methods. (A) Three mice from each group were sacrificed at 5, 11 and 23 days p.i. in one experiment and five mice from each group were sacrificed at each time point in the second experiment. The results from the two experiments were pooled. (B) Four mice from each group were sacrificed at 1,3, 5, 8 and 11 days p.i. Viral titers were determined using a plaque assay. Open circles, virus titers isolated from each eye of infected wild-type (C57BL/6) mice; solid circles, virus titers isolated from each eye of infected PKO mice. Horizontal bars indicate the mean viral titer.