Table 1. Serial change in thromboelastography parameters before and after andexanet alfa administration.

Reference range: CK-R, 4.6-9.1 minutes; CKH-R, 4.3-8.3 minutes; CK-MA, 52-69 mm; CFF-MA, 15-32 mm.

AA = andexanet alfa; CPB = cardiopulmonary bypass; CK-R = citrated kaolin-reaction time; CKH-R = citrated kaolin heparinase-reaction time; CK-MA = citrated kaolin-maximal amplitude; CFF-MA = citrated functional fibrinogen-maximal amplitude

	Before CPB	Intraoperative (before chest closure)	Postoperative (before AA administration)	After AA administration
CK-R (minutes)	26.0	14.3	19.9	7.3
CKH-R (minutes)	10.1	13.2	18.8	7.5
CK-MA (mm)	49.6	56.4	48.8	53.1
CFF-MA (mm)	20.8	20.8	23.7	20.0