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. 2024 Jul 10;19:6945–6980. doi: 10.2147/IJN.S467876

Figure 9.

Figure 9

THP-PSA NPs mechanism of action.235 (Reprint with permission from Feng J, Xiang L, Fang C, et al. Dual-targeting of tumor cells and tumor-associated macrophages by palmitic acid modified albumin nanoparticles for antitumor and antimetastasis therapy. ACS Appl Mater Interfaces. 2022;14(13):14887–14902. Copyright (2022) American Chemical Society.235

Abbreviations: THP-PSA NPs, palmitic acid-modified human serum albumin nanoparticles; M2-TAMs, M2-tumor-associated macrophages; IL-10, interleukin-10; TGF- β1, transforming growth factor-β1; IL-12p70, interleukin-12p70; TNF- α, tumor necrosis factor α; IFN- γ, Interferon γ; MDSCs, Myeloid-derived suppressor cells.