Table 1.
Polymer | Mechanism | NP | Diameter | Preparation Techniques of Nanoparticles | Ref |
---|---|---|---|---|---|
PEG | Coupled with the active amino group on the surface of albumin | PEGylation of HSA-NPs | 120~150 nm | Desolvation | [84] |
PEG | Coupled with the active amino group on the surface of albumin | PEG conjugated onto the Cys-34 residue of HSA loaded with PTX | PEG5k:105 nm PEG20k: 141 nm |
Self-assemble | [85] |
PEG | Coupled with the active amino group on the surface of albumin | Apatinib-loaded HSA-PEG5k | Before and after lyophilization were 131.7 ± 3.5 and 169.6 ± 5.2 nm | Emulsification | [86] |
PEG | Coupled with the active amino group on the surface of albumin | HSA-PEG5k-NP loaded with PTX | 176 ± 3.6 nm | Self-assemble | [87] |
Chitosan | Electrostatic adsorption | Chitosan -coated BSA-NPs loaded with Tetrandrine | 237.9 ± 3.61nm | Desolvation | [88] |
Chitosan | Electrostatic adsorption | Chitosan-BSA nanoparticles loaded with abaloparatide and acetylsalicylic acid | 289 ± 34 nm | Desolvation | [89] |
Chitosan | Electrostatic adsorption | Reduced bovine serum albumin and glycol chitosan nanoparticles loaded with PTX | 349 ± 26 nm | Self-assemble | [90] |
Chitosan | Electrostatic adsorption | Chitosan -coated-HSA loaded with gemcitabine | 200 ± 4 nm | Desolvation | [91] |
PEI | Electrostatic adsorption | BSA-PEI NPs for efficient delivery of CRISPR/Cas9 system | 102.50 nm | – | [92] |
PEI | Electrostatic adsorption | PEI-HSA-NPs loaded with chlorhexidine | 465.2 ± 11.3 nm | Desolvation | [93] |
PEI | Electrostatic adsorption | BSA-PEI was utilized to modify gold nanospheres (AuNSs) and gold nanorods (AuNRs) | 200 nm | – | [94] |
PEI | Electrostatic adsorption | ε-caprolactone modified polyethylenimine-OVA NPs | Around 200 nm | Self-assemble | [95] |
PEI | Electrostatic adsorption | pGL3 plasmid-PEI-coated HSA NPs | 191 ± 4 nm | Desolvation | [96] |
Polycation/polyanion deposition | Albumin surface coating | Poly(arginine) (pARG) and poly (ethylene glycol)-block-poly (L-aspartic acid)-based nab-PTX nanoparticles | 100~140 nm | Desolvation | [97] |
Polycation/polyanion deposition | Albumin surface coating | L-b-L by coating of the HSA-IFN-α NPs with poly(sodium-4-styrene) sulphonate and chitosan | 10 ± 5 nm | pH-condensation | [98] |
Polycation/polyanion deposition | Albumin surface coating | Dox-BSA-NPs with HA and Poly (L-lysine hydrobromide) by LBL | 143 ± 3.79 nm | Desolvation | [99] |
Note: -: no date.
Abbreviations: PEG, Polyethylene glycol; PEI, Polyethylenimine; HSA, human serum albumin; NPs, nanoparticles; BSA, bovine serum albumin; LBL, layer-by-layer; Dox, doxorubicin; PTX, Paclitaxel.