TABLE 5.
Mean prevalence of RV-positive cells during persistent infection detected by ISH using strand-specific 35S-labeled riboprobesa
| Tissue | Euthymic rats
|
Athymic rats
|
||||||
|---|---|---|---|---|---|---|---|---|
| Week 4
|
Week 8
|
Week 4
|
Week 8
|
|||||
| DNA | mRNA | DNA | mRNA | DNA | mRNA | DNA | mRNA | |
| Heart | +/− | +/− | +/− | − | +/− | +/− | +/− | +/− |
| Lung | +/− | +/− | +/− | − | +++ | + | + | +/− |
| Liver | +/− | +/− | − | − | ++ | + | + | +/− |
| Kidney | +/− | +/− | +/− | +/− | + | + | + | +/− |
| Spleen | − | − | − | − | +/− | +/− | +/− | − |
| Lymph nodes | +/− | − | − | − | + | +/− | + | − |
| Small intestine | +/− | +/− | − | − | + | +/− | +/− | +/− |
| Great vessels | +/− | − | +/− | − | + | +/− | +/− | +/− |
| Mesenteric vessels | + | +/− | +/− | − | +++ | + | + | +/− |
| Gonadal vessels | + | +/− | + | +/− | ++ | + | + | +/− |
a
Results are expressed as mean scores for the corresponding tissues from three to six rats per time point. The scoring system is summarized in the footnote for Table 3 and in Materials and Methods.