Table 3.

Common nontoxic ingredients in ocular cosmetics.

Ingredient	Function	Products	Comment
Aluminum powder	cosmetic colorant	around-eye cream, eyeliner, eyeshadow, makeup primer, mascara, moisturizer	no adverse effects related to the eye [911]
Aluminum silicate	abrasive, absorbent, anticaking agent, bulking agent, opacifying agent	serum	no adverse effects related to the eye [912]
Azelaic acid	buffer, pH adjuster	makeup primer, moisturizer, serum	determined safe for use in cosmetics, subject to concentration or use limitations - distinction between safe concentrations in leave-on and rinse-off [236,869,913]
Azulene (chamomile extract)	skin-conditioning	around-eye cream, serum	not expected to be potentially toxic or harmful [871]
Biotin	skin-conditioning	around-eye cream, eyeliner, eyelash glue, makeup primer, makeup remover, mascara, serum	not expected to be potentially toxic or harmful [871]
Bismuth oxychloride	cosmetic colorant	around-eye cream, eyeliner, eyeshadow, makeup primer, mascara, moisturizer, serum	not expected to be potentially toxic or harmful [871]
Hyaluronic acid	hydration	serum, moisturizer, cleanser, around-eye-cream,eyeliner, makeup remover, makeup primer, eyelash glue, mascara	not expected to be potentially toxic or harmful [871]
Isoleucine	skin-conditioning agent	serum, around-eye cream, makeup primer, makeup remover, mascara	not expected to be potentially toxic or harmful [871]
Palmitoyl pentapeptide-4	skin conditioning	serum, around-eye cream, makeup primer, makeup remover, moisturizer	no adverse effects related to the eye
Pomegranate seed oil (plant-based source of punicic acid)	emollient	serum, eyeshadow, moisturizer, around-eye cream, makeup remover	no adverse effects related to the eye
Sodium glycerophosphate	moisturizing agent	makeup primer	not expected to be potentially toxic or harmful [871]
Undecylenoyl phenylalanine	skin-conditioning agent	moisturizer, serum	not expected to be potentially toxic or harmful [914]